diff --git a/.changes/1.43.109.json b/.changes/1.43.109.json
new file mode 100644
index 000000000..6f96fd8d6
--- /dev/null
+++ b/.changes/1.43.109.json
@@ -0,0 +1,7 @@
+[
+  {
+    "category": "``memorydb``",
+    "description": "Update memorydb client to latest version",
+    "type": "api-change"
+  }
+]
\ No newline at end of file
diff --git a/CHANGELOG.rst b/CHANGELOG.rst
index 0d45f4c1f..7ddcbab33 100644
--- a/CHANGELOG.rst
+++ b/CHANGELOG.rst
@@ -2,6 +2,12 @@
 CHANGELOG
 =========
 
+1.43.109
+========
+
+* api-change:``memorydb``: Update memorydb client to latest version
+
+
 1.43.108
 ========
 
diff --git a/botocore/__init__.py b/botocore/__init__.py
index 60a2a5125..3d9f9bbc6 100644
--- a/botocore/__init__.py
+++ b/botocore/__init__.py
@@ -17,7 +17,7 @@ import os
 import re
 from logging import NullHandler
 
-__version__ = '1.43.108'
+__version__ = '1.43.109'
 
 
 # Configure default logger to do nothing
diff --git a/botocore/data/memorydb/2021-01-01/service-2.json b/botocore/data/memorydb/2021-01-01/service-2.json
index 1ffb988c6..c7409833a 100644
--- a/botocore/data/memorydb/2021-01-01/service-2.json
+++ b/botocore/data/memorydb/2021-01-01/service-2.json
@@ -4,8 +4,11 @@
     "apiVersion":"2021-01-01",
     "endpointPrefix":"memory-db",
     "jsonVersion":"1.1",
-    "protocol":"json",
-    "protocols":["json"],
+    "protocol":"smithy-rpc-v2-cbor",
+    "protocols":[
+      "smithy-rpc-v2-cbor",
+      "json"
+    ],
     "serviceAbbreviation":"Amazon MemoryDB",
     "serviceFullName":"Amazon MemoryDB",
     "serviceId":"MemoryDB",
@@ -13,6 +16,7 @@
     "signingName":"memorydb",
     "targetPrefix":"AmazonMemoryDB",
     "uid":"memorydb-2021-01-01",
+    "xmlNamespace":"http://memorydb.amazonaws.com/doc/2021-01-01/",
     "auth":["aws.auth#sigv4"]
   },
   "operations":{
diff --git a/docs/source/conf.py b/docs/source/conf.py
index 20f09b7d3..50f46a710 100644
--- a/docs/source/conf.py
+++ b/docs/source/conf.py
@@ -59,7 +59,7 @@ copyright = f'{current_year}, Amazon Web Services, Inc'
 # The short X.Y version.
 version = '1.43.1'
 # The full version, including alpha/beta/rc tags.
-release = '1.43.108'
+release = '1.43.109'
 
 # The language for content autogenerated by Sphinx. Refer to documentation
 # for a list of supported languages.